Neocell

STREPTOMYCIN Injectable solution

COMPOSITION (per ml):  
Streptomycin base (as sulfate)………………………………..….…..125 mg
Dihydrostreptomycin base (as sulfate )…………………………….. 125 mg

PHARMACOLOGICAL PROPERTIES
Streptomycin Tetoros is indicated for the treatment of infections caused  by bacteria as Streptococcus, Staphylococcus, Pasteurella, Brucella, Haemophilus, Colibaccilus, Aerobacter aergenes, Paracolon, Erycilopethrix, Corynebacteriae, Leptospira, Klebsiella.

TARGET SPECIES
Dogs, cats.

INDICATIONS
The product is suitable for the treatment of infections caused by bacteria, as Streptococcus, Staphylococcus, Pasteurella, Brucella, Haemophilus, Colibaccilus, Aerobacter aergenes, Paracolon, Proteus, Shigella, Pseudomonas aeruginusa, Vibrions, Listeria, B.Anthracis, Erycilopethrix, Corynebacteriae, Leptospira, Klebsiella., Salmonella, PPLO.

DOSAGE AND METHOD OF ADMINISTRATION
The product is administered intramuscularly, or subcutaneously. The intramuscular injection should be done deeply and slow.
Dogs, Cats: 1 ml per 25 kg of body weight /12 hours for 3 consecutive days at least. It is recommended the revise of treatment after 9-10 days with the same dosage, at the persistent cases. During the administration of vitamins, it is recommended the simultaneous administration of ratio with high concentration in metallic salts.

CONTRAINDICATIONS
In cases of renal damages, streptomycin is not eliminated in normal rate with result its concentration. So, the product shouldn’t be administered to animals that present sensitivity or suffer by renal insufficiency.
Also, it is not advised the use of streptomycin to animals sensitive to it.

UNDESIRABLE EFFECTS
It is possible the animals to present symptoms of hypersensitivity by having difficulty in breathe, oedema at head or at acroteria, salivation and general malaise. In those cases, the administration of the medicine is stopped and is administered epinephrine and antihistaminics. Also, great quantities of STREPTOMYCIN-TETOROS and enduring administration can cause irritation of kidney, dizziness, or deafness due to toxic action on the 8th cranium nerve.

INTERACTION WITH OTHER MEDICAMENTS
The muscle- relaxant action of streptomycin can be increased with simultaneous administration of similar substances, as general anaesthetics, magnesium compound and muscle-relaxant. It is possible to notice cardiovascular inhibition during general anaesthesia with barbiturate. This action can be reversed by intravenous administration of calcium chloride. The nephrotoxic action of Streptomycine can be increased with simultaneous administration of aminoglycosides, or any other substance with nephrotoxic action. The ototoxic action of streptomycin can be increased by the administration of diuretic acting at Henle’s loop.

INCOMPATIBILITY
Not mentioned

OVERDOSE
Has not been observed.

USE DURING PREGNANCY AND LACTATION
It has not been observed neurotoxic reaction. The product is not administered during the last month of pregnancy, so as to ensure the normal development of the embryo.

SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE PRODUCT TO ANIMALS
Persons, who use the product, may have itch on their fingers and symptoms of eczema at their hands and face. Attentive washing of hands is advisable after the use of the product

WITHDRAWAL TIME
Not applicable

STORAGE - SHELF LIFE
18 months from production date in cool place. After the first opening can be used within 30 days provided it is stored in temperature < 25^o C

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIAL, IF ANY:
Are not required

PACKAGE
Flacons of 50 ml and 100 ml