Presentation
Divamectin® 1% injection is a clear, colourless solution for injection for cattle, sheep
and pigs.
It contains 10mg/ml ivermectin.
Indications
Cattle (beef and non-lactating dairy cattle)
For the treatment of infections with the following parasites
Gastrointestinal worms (adults and 4th stage larvae):
Ostertagia ostertagi
Ostertagia lyrata
Haemonchus placei
Trichostrongylus colubriformis
Cooperia oncophora (adults)
Cooperia punctata (adults)
Cooperia pectinata (adults)
Bunostomum phlebotomum
Oesophagostomum radiatum
Lungworms (adult and 4th stage larvae):
Dictyocaulus viviparus
Eyeworms (adult):
Thelazia spp.
Warble flies (parasitic stages):
Hypoderma bovis
H. lineatum
Mites:
Psoroptes ovis
Sarcoptes scabiei var. bovis
May also be used as an aid in the control of the mange mite Chorioptes
bovis but complete elimination may not occur.
Sucking lice:
Linognathus vituli
Haematopinus eurysternus
Solenopotes capillatus
Treatment with Ecomectin 10 mg/ml Solution for Injection at the recommended dose
rate prevents re-infection with
This datasheet offers general information. Please contact your local ECO representative for
country-specific details.
- Haemonchus placei, Cooperia oncophora, Cooperia pectinata and
Trichostrongylus axei for 7 days after treatment,
- Ostertagia ostertagi and Oesophagostomum radiatum for 14 days after
treatment and
- Dictyocaulus viviparus for 21 days after treatment.
Sheep
For the treatment of infections with the following parasites
Gastrointestinal roundworms (adults):
Ostertagia circumcincta
Haemonchus contortus
Trichostrongylus axei
T. colubriformis and T. vitrinus
Cooperia curticei
Nematodirus filicollis
Variable activity may be observed against Cooperia curticei and
Nematodirus filicollis.
Lungworms:
Dictyocaulus filaria (adults)
Mange mites:
Psoroptes ovis
Nasal bot:
Oestrus ovis (all larval stages)
Pigs
For the treatment of infections with the following parasites
Gastro-intestinal worms (adult and fourth stage larvae):
Ascaris suum
Hyostrongylus rubidus
Oesophagostomum spp.
Strongyloides ransomi (adults).
Lungworms:
Metastrongylus spp. (adults)
Lice:
Haematopinus suis
Mange Mites:
Sarcoptes scabiei var. suis
Dosage and administration
For single administration only (except for the treatment of Psoroptes ovis infections in
sheep).
Cattle
Dosage:
1.0 ml per 50 kg bodyweight (based on a recommended dosage level of 200
micrograms ivermectin per kg bodyweight).
Administration:
Inject subcutaneously in front of, or behind, the shoulder using aseptic technique. A
sterile 1.4 x 15 mm (17G x ½ inch) needle is recommended.
This datasheet offers general information. Please contact your local ECO representative for
country-specific details.
Sheep
Dosage:
0.5 ml per 25 kg of bodyweight (based on a recommended level of 200 micrograms
ivermectin per kg bodyweight).
Administration:
For the treatment of gastrointestinal roundworms, lungworms and nasal bots inject
once subcutaneously in the neck, using aseptic precautions; a sterile 1.4 x 15 mm
(17G x ½ inch) needle is recommended. For the treatment of
Psoroptes ovis (sheep scab), two injections with a seven day interval are required to
treat clinical signs of scab and to eliminate living mites.
For young lambs weighing less than 20.0 kg give 0.1 ml per 5 kg. In these lambs the
use of a syringe which can deliver as little as 0.1 ml is recommended.
Pigs
Dosage:
1.5 ml per 50 kg bodyweight (based on a recommended dosage level of 300
micrograms ivermectin per kg bodyweight)
Administration:
The recommended route of administration is by subcutaneous injection into the neck
using aseptic technique and a sterile 1.4 x 15 mm (17G x ½ inch) needle.
For piglets weighing less than 16 kg give 0.1 ml per 3 kg. In these piglets the use of a
syringe which can deliver as little as 0.1 ml is recommended.
Withdrawal period
Cattle
Meat and offal: 49 days within EU. 42 days for all countries and regions outside EU.
Do not use in lactating cows producing milk for human consumption. Do not use in
non-lactating dairy cows, including pregnant dairy heifers, within 60 days of calving.
Sheep
Meat and offal: 42 days.
Do not use in lactating ewes producing milk for human consumption. Do not use in
sheep which are intended to produce milk for human consumption within 60 days of
lambing.
Pigs
Meat and offal: 28 days
Operator warnings
- Do not smoke, eat or drink while handling the product.
- Wash hands after use.
- Take care to avoid self injection: the product may cause local irritation and/or pain at the site of injection.
- Swab septum before removing each dose.
- When using the 200 or 500ml pack sizes, use only automatic syringe equipment.
the syringe, use of a draw-off needle is recommended to avoid excessive
broaching of the stopper.
Pharmaceutical precautions
Do not store above 25ºC.
Protect from direct light.
Store in tightly closed, original container.
Store in original carton.
Shelf-life: 3 years
Following withdrawal of the first dose, use the product within 28 days
General precautions
Keep out of reach and sight of children. For animal treatment only.
Extremely dangerous to fish and aquatic life. Do not contaminate surface waters or
ditches with the product or used container.
Container disposal
Any unused product or waste material should be disposed of in accordance with
national requirements.
Package quantities
Fluorinated HDPE multidose container with bromobutyl rubber stopper and
aluminium cap.
Pack size: 50 ml, 200 ml and 500 ml.
Further information
Avermectins may not be well tolerated in all non-target species. Cases of intolerance
with fatal results are reported in dogs – especially Collies, Old English Sheepdogs
and related breeds and crosses, and also in turtles/tortoises.
Do not combine treatment with vaccination against lungworms. If vaccinated animals
are to be treated, treatment should not be carried out within a period of 28 days
before or after vaccination.
The shedding of nematode eggs can continue for some time after treatment.
In Cattle: To avoid secondary reactions due to the death of Hypoderma larvae in the
oesophagus or in the spine, it is recommended to administer the product at the end
of warble fly activity and before the larvae reach their resting sites.
Frequent and repeated use may lead to the development of resistance. It is important
that the correct dose is given in order to minimise the risk of resistance. To avoid
under-dosing, animals should be grouped according to their bodyweight and dosed
according to the dose of the heaviest animal in the group.
Clinical symptoms of ivermectin toxicity include ataxia and depression. No antidote
has been identified. In case of overdose, symptomatic treatment should be given. No
signs of toxicity were observed in animals treated at up to 3 times the recommended
dose rate.
Soft tissue swelling and thickening of the skin at the injection site has been observed
in treated animals. Typically, these reactions are transient and disappear within four
weeks.
Transitory discomfort has been observed in some animals, immediately following
subcutaneous administration. In cattle this may include jumping and rolling, but
behaviour returns to normal after 15 minutes.
